Looks like Destiny if it wasn't held back by the Xbox 360 and PS3.
Final game they showed was Spider-Man. Pretty impressive. It's like if Spider-Man 2 was made today with some influences from other recent Spidermangs and Batmangs.
This is what we know so far:
-Fisk (Kingpin is in jail)
-Saw an Osborn billboard (didn't get to read it but was probably about him runnign for president, maybe we'll get soem Dark Avengers stuff? Probably not)
-Mr. Negative (this is the guy that created Anti-Venom)
-Miles (black kid Spider-man)
-Cool easter egg, they recreated that scrapped movie scene that used the Twin Towers afetr 9/11 happened where a helicopter was trapped between two buildings with Spidey's webs